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By R. M. Shaw, R. A. Bowen, G. E. Paget

ISBN-10: 0433285001

ISBN-13: 9780433285007

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Example text

The concept that cancer is an irreversible state, D 42 SIR STANFORD CADE independent and uncontrollable, is obviously no longer true. It can be controlled by physiological means ; it is dependent on normal phenomena; it relies on its environment for survival. This concept of hormone dependence has led to an entirely new method of treatment. To the time-honoured methods of treatment—'cut it out', 'burn it out', 'poison it', methods which aimed at the direct attack on cancer with the object of destroying it—has been added an indirect attack, the weapon of physiological warfare against cancer.

Different tumours require not only different drugs but different schedules of treatment. The results of chemotherapy can also be improved or the period of effectiveness prolonged by the combination of several drugs. These should be chosen for their difference of mode of action and given either together to potentiate one another or in sequence to overcome drug resistance. The use of specific antidotes such as folinic acid and methotrexate, the preservation of autologous bone marrow with a view to marrow transfusion are refinements which permit a more radical chemotherapeutic attack.

Both interpretation and recapitulation of verbally presented material may be poor, particularly when interlocking or consecutive themes are concerned, and when references are allusive or ambiguous. The patient may fail to paraphrase such commonplace slogans as 'Players please', or wise saws like 'easy come, easy go', 'still waters run deep', or 'a bird in the hand'. This failure may be due to a defect either in comprehension or in explanation (Zangwill, 1964), or in both. In attempting to repeat a couple of consecutive jokes or fables, the patient may confuse the two propositions, and contaminate his narrative with inappropriate ideas and words.

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All Heal. A Medical and Social Miscellany by R. M. Shaw, R. A. Bowen, G. E. Paget

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